Studies

The CTN+ supports clinical trials to find new ways to prevent, treat and manage HIV and other STBBIs, prioritizing a community-based approach of the highest scientific and ethical standards.

Virologic control of HIV: Switching from cART to Triumeq

Completed

Treatment & Management

CTN 288: LHIVE Healthy

Evaluation of web-based interventions to support people living with HIV in the adoption of health behaviours

Reporting

Prevention & Testing

CTNPT 003: Bone and renal outcomes in tenofovir exposed infants

Bone and renal outcomes in HIV-exposed uninfected infants with perinatal exposure to tenofovir

Completed

Prevention & Testing

CTN 284: WelTel Retain

Promoting Engagement in Pre-ART HIV Care Through SMS

Ongoing

Treatment & Management

BC & Yukon Region

Ontario Region

CTN 292A: Screening for high-grade anal dysplasia in HIV+ MSM

Development and validation of an anal cancer screening algorithm in HIV-positive men who have sex with men (MSM) – part of HPV-SAVE study.

Completed

Prevention & Testing

CTNPT 013: Sexual health and HIV-risk management in MSM

The impact of in-clinic follow-up with a sexologist on the sexual health of HIV-serodiscordant MSM couples

Terminated

Treatment & Management

CTNPT 019: Improving outcomes with Metformin

Can metformin prevent the progression of liver fibrosis in HCV-HIV co-infected and HCV mono-infected patients with insulin resistance?

Terminated

Cure & Immunotherapies

CTNPT 020: Therapeutic HIV vaccine with early HAART treatment initiation

A pilot randomized, open label study to evaluate the effect of a therapeutic HIV vaccine consisting of PENNVAX®-GP (gag, pol, env) and INO-9012 DNA vaccine delivered via electroporation on reducing HIV viral reservoirs in infected individuals, who initiated therapy during the acute/early phase of infection

Terminated

Cure & Immunotherapies

CTNPT 022A: PROOV IT I

Probiotic Visbiome for Inflammation and Translocation in HIV (PROOV IT I)

Reporting

Cure & Immunotherapies

CTNPT 022B: PROOV IT II

Probiotic supplements for gut immune health (PROOV IT II)

Reporting

Treatment & Management

CTNPT 024: Non-alcoholic steatohepatitis in HIV mono-infection

Use of non-invasive methods for diagnosis of non-alcoholic steatohepatitis (NASH) in HIV patients and therapeutic use of vitamin E

Reporting

Treatment & Management

CTN 283: the I-Score Study

The development and validation of a patient-reported measure of antiretroviral therapy’s interference with life: a clinical patient-management tool for healthcare providers

Careers

Interested in joining our team? Here are the current career opportunities with the CTN+ and our collaborators. For Fellowship opportunities, please visit our Postdoctoral Fellowship program page.

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